Lamivudine or lamivudine combined with hepatitis B immunoglobulin in prophylaxis of hepatitis B recurrence after liver transplantation: a meta-analysis
نویسندگان
چکیده
منابع مشابه
Is Hepatitis B Immunoglobulin Necessary in Prophylaxis of Hepatitis B Recurrence after Liver Transplantation? A Meta-Analysis
BACKGROUND & AIMS Application of nucleoside analogues and hepatitis B immunoglobulin (HBIG) has reduced hepatitis B virus (HBV) recurrence rate after liver transplantation (LT) dramatically. Recent data suggests therapy without HBIG is also effective. We sought to evaluate the necessity of HBIG in prophylaxis of HBV recurrence after LT. METHODS A meta-analysis was performed. PubMed/MEDLINE, W...
متن کاملA multicenter study of lamivudine treatment in 33 patients with hepatitis B after liver transplantation.
Hepatitis B virus (HBV) infection after liver transplantation (LT) may lead to severe and rapidly progressive graft failure. Antiviral treatment may be of benefit in selected patients with recurrent hepatitis B post-LT. The aim of this prospective open-label study is to determine the safety and efficacy of lamivudine in 33 liver transplant recipients with active HBV infection. The median time f...
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conclusions etv and lam treatments had similar effects to improve 24 weeks survival rate of patients with chb-associated liver failure, but etv was associated with greater clinical improvement. both drugs were tolerated well during the treatment. it is suggested to perform further studies to verify the results. background nucleoside analogues are recommended as antiviral treatments for patients...
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Lamivudine monoprophylaxis against hepatitis B virus (HBV) reinfection after liver transplantation is associated with recurrence due to escape mutants and second generation recombinant HBV vaccine is not effective. We studied the efficacy of two courses each of three double-doses (20 microg) of third-generation recombinant pre-S containing vaccine (Sci-B-Vac) in 20 patients on lamivudine prophy...
متن کاملEntecavir Versus Lamivudine Therapy for Patients With Chronic Hepatitis B-Associated Liver Failure: A Meta-Analysis
BACKGROUND Nucleoside analogues are recommended as antiviral treatments for patients with hepatitis B virus (HBV)-associated liver failure. Clinical data comparing entecavir (ETV) and lamivudine (LAM) are inconsistent in this setting. OBJECTIVES To compare the efficacy and safety of ETV and LAM in patients with chronic hepatitis B (CHB)-associated liver failure. PATIENTS AND METHODS A liter...
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ژورنال
عنوان ژورنال: Transplant International
سال: 2009
ISSN: 0934-0874,1432-2277
DOI: 10.1111/j.1432-2277.2008.00784.x